Pilot Program Applications
THE PILOT PROGRAM APPLICATION IS NOW OPEN UNTIL FRIDAY, MARCH 22 BY 5:00 PM (CST)
The African American Pharmacogenomic Consortium Network Transdisciplinary Collaborative Center (ACCOuNT TCC) was created to: 1) establish an African Ancestry pharmacogenomics research network to facilitate genomic research and to establish a public genomics resource for continued translational research; 2) establish mechanisms to support implementation, diffusion, and continuing evaluation and improvement of precision medicine in African Americans; and 3) engage community leaders in African American pharmacogenomic research. As part of this commitment, ACCOuNT will provide funding for a pilot grant program that will accelerate the uptake of cardiovascular pharmacogenomics research findings among community physicians and patients.
Two projects focused on African American cardiovascular pharmacogenomics, or how a person’s genes impact their reaction to drugs for the heart and blood vessels, will be awarded each year. Awards will be made for up to $25,000 for each project.
2019 Pilot Grant Awardees
Educating African American Nurse Community Leaders to Advance and Promote Diversity in Cardiovascular Pharmacogenomics Research
Grantee: Southern Nevada Black Nurses Association (SNBNA) and Harvard Pilgrim Health Care Institute & Harvard Medical School
Target Audience: Members of the National Black Nurse Association (NBNA)
Goals: 1) Explore and disseminate concerns about precision medicine research based on the perspectives of African American nurse community members who are engaged or have interest in engaging in precision medicine research. 2) Educate the African American nurse community on key topics in cardiovascular pharmacogenomics research, as a focus area of precision medicine with the intent to improve NBNA interest in participating in precision medicine research programs.
Intervention: Semi-structured phone interviews with NBNA chapter members and webinars with educational modules and curriculum for the NBNA community
Measures: 1) Number of concerns about precision medicine research and strategies to address concerns as identified through NBNA interviews, 2) number of webinar attendees, and 3) post webinar surveys
Expected Impact: Increased interest in precision medicine research among NBNA community members.
2018 Pilot Grant Awardees
Cardiovascular Pharmacogenomics in Community Dwelling Older Adults
Grantee: Virginia Commonwealth University: Institute for Inclusion, Inquiry and Innovation- Health and Wellness in Aging Core
Target Audience: Community Dwelling Older African Americans
Goals: 1) Increase the awareness of community participants about genetic screening, 2) Increase the proportion of community participants with heart disease asking their doctors about genetic testing for heart medications, 3) Increase the number of doctors in community settings who are knowledgeable about genetic screening for heart medications
Intervention: 1) Recruitment from a long standing free service, 2) Wallet sized cards that can be kept with the Medicare or insurance cards, 3) Consultations for the wallet cards that contain Pharmacogenomic results for participants
Measures: Pre/post counseling surveys
Impact: Increase screening for cardiovascular genetic variants in the African American population
Impact of Educating Medical Professionals and Patients on the Need for Pharmacogenetic Testing in the African-American Community
Grantee: C. W. Williams Community Health Center (CWWCHC) located in Charlotte, NC
Target Audience: African-American identified or of African descent that are 18 years or older
Goals: 1) Increasing awareness and knowledge among providers and the at-large African American community regarding the benefits of pharmacogenetic testing, clinical research, and the use of medications in patients with specific cardiovascular genetic variants, 2) provide pharmacogenetic testing to screen for cardiovascular genetic variants, 3) Lessen barriers to participating in pharmacogenetic testing in the African-American community by increasing access to testing and future research studies.
Intervention: Facilitate workshops to educate providers (minimum two workshops) and community members/patients (minimum two workshops) about pharmacogenetic tests and their benefits as one intervention. CWWCHC providers will administer pharmacogenetic test for participating patients, with the target number of 45 tests.
Measures: 1) Pre/post surveys will be administered to participants, 2) analyzing electronic health records and pharmacogentic tests, and 3) collect and review patient interest logs
Impact: The primary goal is to improve the health outcomes for African-American residents in CWWCHC’s service area through increased screening for cardiovascular genetic variants.
2017 Pilot Grant Awardees
Educating Federally Qualified Health Center (FQHC) Providers to Advance Pharmacogenomics and Research Participation in Diverse Settings
Grantee: University of Pittsburgh/University of Illinois – Chicago
Target Audience: Primary care providers and community advisory board members of an FQHC caring for a majority African American population on the West Side of Chicago
Goals: 1) Increase provider and patient understanding of pharmacogenetics at an FQHC in Chicago, 2) Enhance therapeutic decision-making in African American patients by increasing awareness of ethnic specific genetic variants which can impact pharmacokinetics and pharmacodynamics, and 3) Increase recruitment into the All Of Us Research Program through enhanced education of providers and community leaders through Test2Learn.
Intervention: Implementation of Test2Learn curriculum, an interactive pharmacogenetics education program developed at the University Of Pittsburgh School Of Pharmacy with primary care providers and lay community advisory board members
Measures: Pre/post knowledge testing
Impact: Increased provider knowledge and practice regarding cardiovascular pharmacogenomic prescribing, with community advisory board members serving as community advocates for pharmacogenomic testing
African American Pharmacogenomics and Precision Medicine Learning Events (APPLES)
Grantee: Taking Effective Action, Inc, Bowie, MD (Prince George’s County/DC Area)
Research/Evaluation support: Carla D. Williams, PhD, Howard-Georgetown Clinical and Translational Sciences Institute
Target Audience: African American faith leaders and congregants
Goal: To increase knowledge and awareness of cardiovascular pharmacogenomics and precision medicine among African Americans in Washington, D.C., and Prince George’s County, Maryland
Interventions: 1) Create a 2-4 minute culturally relevant interactive video tutorial and companion brochure with content on cardiovascular health, pharmacogenomics, precision medicine and African American involvement in medical research during the first two months of the program, 2) Conduct at least 5 learning sessions at area churches and community organizations in the metropolitan D.C. area between March and December 2018, reaching at least 400 residents and church leaders, 3) Distribute the video tutorial via social media, email and websites and receive at least 250 views between March and December 2018, and 4) Exhibit at the 2018 NBC4 Health and Fitness Expo in Washington, D.C., on March 10-11, 2018, and conduct short trainings in the exhibit booth with at least 200 attendees
Measures: Number of attendees at events, pre/post testing for knowledge and understanding of concepts, and number of web viewings with post-viewing survey
Impact: Enhance health offerings of partner faith institutions and increase awareness and importance of pharmacogenomics.
Watch the final video “How Geonomics May Help You Receive a Better Prescription”