ACCOuNT Leadership

Minoli Perera
Minoli Perera, PharmD, PhD, Northwestern University

Dr. Perera is a Principal Investigator for ACCOuNT, Co-leader of the Administrative Core, and PI of the Discovery Project. An Associate Professor of Pharmacology at Northwestern University, she is a recognized expert in the field of African American pharmacogenomics and was a lead member in the International Warfarin Pharmacogenomic Consortium (IWPC). She is currently a Member of the Clinical Pharmacogenomics Implementation Consortium (CPIC), which is constructing the newest pharmacogenomics guidelines for warfarin implementation, and was recently awarded the Leon Goldberg Young Investigator award for her outstanding contribution to both clinical pharmacology and minority pharmacogenomics.

meltzerDavid Meltzer, MD, PhD, University of Chicago

Dr. Meltzer is the co-Principal Investigator for ACCOuNT and a Core Lead for the Administrative and Implementation Cores. He is Chief of the Section of Hospital Medicine, Director of the Center for Health and the Social Sciences, and Chair of the Committee on Clinical and Translational Science at The University of Chicago, where he is Professor in the Department of Medicine, and affiliated faculty of the Harris School of Public Policy Studies and the Department of Economics. Meltzer’s research explores problems in health economics and public policy with a focus on the theoretical foundations of medical cost-effectiveness analysis and the cost and quality of hospital care. Meltzer has performed randomized trials comparing the use of doctors who specialize in inpatient care (“hospitalists”). He is currently leading a Centers for Medicaid and Medicare Innovation Challenge award to study the effects of improved continuity in the doctor patient relationship between the inpatient and outpatient setting on the costs and outcomes of care for frequently hospitalized Medicare patients. He led the formation of the Chicago Learning Effectiveness Advancement Research Network (Chicago LEARN) that helped pioneer collaboration of Chicago-Area academic medical centers in hospital-based comparative effectiveness research and the recent support of the Chicago Area Patient Centered Outcomes Research Network (CAPriCORN) by the Patient Centered Outcomes Research Institute (PCORI).

MillerDoriane Miller, MD, University of Chicago

Dr. Doriane Miller is the Consortium Core Lead and an Associate Professor of Medicine and Center for Community Health and Vitality Director. Dr. Miller has been providing care to under-served minority populations for more than 20 years. In addition to her role as a primary care physician, she has a special interest in behavioral health. Under her leadership, physicians, educators and community members work to improve population health outcomes for residents on the South Side of Chicago through community-engaged research, demonstration and service models. Dr. Miller’s research focuses on the intersection of health disparities and race. She has served as the project director for several studies designed to augment care by promoting collaboration among physicians, patients and families. Dr. Miller’s work in the area of improving asthma outcomes through school and community interventions was noted by the American Academy of Asthma, Allergy and Immunology with a 2006 Special Recognition Award.

robert-grossman-print-2013Robert Grossman, PhD, University of Chicago

Dr. Robert Grossman is the Lead for the Data Analysis and Harmonization Core. He is a faculty member in the Section of Genetic Medicine, as well as the Chief Research Informatics Officer for the Division of the Biological Sciences and a senior fellow in the Computation Institute and the Institute for Genomics and Systems Biology. His research group focuses on bioinformatics, data mining, cloud computing, data intensive computing, and related areas. He is also the founder of Open Data Group, which has provided strategic consulting and outsourced services in analytics since 2002, specializing in building predictive models over big data. His current research is focused on bioinformatics, especially developing systems, applications, and algorithms so that large datasets of genomics data can be integrated with phenotype information extracted from electronic medical records and analyzed to deepen our understanding of diseases.

20100729-o'donnell-peter-physicianportraitPeter H. O’Donnell, MD, University of Chicago

Dr. Peter H. O’Donnell is an Assistant Professor of Medicine in the Department of Medicine and project lead for the Translational Project. He specializes in the treatment of genitourinary malignancies, including prostate, kidney, and testicular cancers — with particular expertise in bladder cancer. Dr. O’Donnell is a well-published researcher with advanced training in pharmacology and pharmacogenomics (the study of genetic traits that cause differences between patients in drug responses and side-effects). He has an interest in the study of personalized medicine, which involves considering each patient’s genetic profile when determining chemotherapy and other therapeutic decisions. Dr. O’Donnell has several ongoing research projects. Currently, he is investigating how genetic factors affect chemotherapy drug outcomes — specifically for patients receiving treatment for bladder cancer, and for patients receiving the widely used chemotherapy drugs cisplatin and capecitabine.

Program Management

Paula Friedman_NorthwesternPaula Friedman, PhD, Northwestern University

Dr. Paula Friedman is the ACCOuNT Program Manager. Dr. Friedman, previously the Associate Director of Scientific Collaborations for the University of Chicago’s Center for Personalized Therapeutics (CPT), is an experienced project manager who is a molecular biologist by training. Dr. Friedman managed all research projects for the CPT, which included the Pharmacogenomics of Anticancer Agents Research Group (PAAR), a research group within the Pharmacogenomics Research Network (PGRN). Dr. Friedman provides overall support to ACCOuNT and to each individual core and research project.

Lexi NashAlexa Nash, Northwestern University

Lexi Nash is the ACCOuNT Project Administrator. Ms. Nash is the Program Assistant for the Department of Pharmacology at Northwestern University and will devote her time to the Administrative Core. She will assist Drs. Perera and Friedman, as well as any of ACCOuNT’s investigators in all administrative functions. She is responsible for helping with all financial aspects of the grant, assisting in preparing progress reports, and organizing all meetings, teleconferences, and videoconferences.

Site Principal Investigators

Arthur Harralson

Arthur Harralson, PharmD
Shenandoah University
Project: Discovery

Teri Klein

Teri Klein, PhD
Stanford University
Project: Discovery

Edith Nutescu

Edith Nutescu, PharmD
University of Illinois at Chicago
Projects: Discovery and Translation
Travis O'Brien
Travis O’Brien, PhD
George Washington University
Project: Discovery
Kevin J. O'Leary
Kevin J O’Leary, MD
Northwestern University
Project: Translation

Matthew Tuck.jpg

Matthew Tuck, MD
Washington, DC, VA Medical Center
Project: Discovery

Scientific Advisory Committee

Rex Chisholm, PhD, Northwestern University
James Liao, MD, University of Chicago
Howard McLeod, PharmD, Moffitt Cancer Center
Mark Ratain, MD, University of Chicago